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Brain Wash

Brain Wash

Detox Your Mind for Clearer Thinking, Deeper Relationships, and Lasting Happiness
by David Perlmutter 2020 304 pages
3.80
2k+ ratings
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Key Takeaways

1. Modern Life Disconnects Us from Our True Selves and Wellbeing

"We are left feeling inadequate. It's time to reconnect to our brains' higher levels of thinking and functioning."

Disconnection syndrome plagues modern society. Our brains are constantly bombarded with stimuli designed to exploit our psychology, from addictive junk food to endless social media scrolling. This leads to chronic stress, inflammation, and impaired decision-making. The result is a population that feels isolated, anxious, and unfulfilled despite material abundance.

The authors argue this disconnection stems from an overactive amygdala (our emotional, reactive brain center) and an underutilized prefrontal cortex (our rational, executive functioning center). By understanding how our brains are being hijacked, we can take steps to regain control and cultivate lasting wellbeing. The book outlines a holistic approach to "rewiring" our brains through diet, sleep, exercise, nature exposure, mindfulness, and social connection.

2. The Prefrontal Cortex is Key to Higher Thinking and Emotional Regulation

"The prefrontal cortex orchestrates thoughts and actions that help us achieve our goals, from simple objectives such as cooking a meal to complex tasks such as writing a book."

The prefrontal cortex enables:

  • Executive function
  • Planning and decision-making
  • Impulse control
  • Emotional regulation
  • Empathy and social behavior

A healthy prefrontal cortex allows us to override impulsive urges, think long-term, and make decisions aligned with our values and goals. However, chronic stress, poor diet, lack of sleep, and other modern factors can impair prefrontal cortex function. This leaves us more susceptible to reactive, emotional decision-making driven by the amygdala.

The good news is that we can strengthen our prefrontal cortex through lifestyle changes. Mindfulness meditation, nature exposure, exercise, and quality sleep have all been shown to enhance prefrontal cortex activity and connectivity.

3. Chronic Stress and Inflammation Hijack Our Brain's Decision-Making

"Stress is like fuel for the amygdala and poison for the prefrontal cortex."

Chronic stress impacts the brain by:

  • Increasing activity in the amygdala
  • Decreasing activity in the prefrontal cortex
  • Elevating inflammatory markers
  • Impairing memory and learning
  • Increasing risk of anxiety and depression

Our bodies evolved for short bursts of acute stress, not the chronic low-level stress common in modern life. This ongoing stress response keeps us in a state of heightened reactivity and impairs our ability to think clearly and make good decisions.

Inflammation, often triggered by chronic stress and poor diet, further compounds these effects. It can lead to structural changes in the brain that make us more impulsive and emotionally reactive. Breaking this cycle requires addressing both the sources of stress/inflammation and actively cultivating prefrontal cortex function through healthy lifestyle choices.

4. Digital Technology Exploits Our Reward Systems and Impairs Focus

"Your attention and your decisions are sold to the highest bidder, to companies with the best understanding of how to manipulate your psychology and biology for their own profit."

Digital addiction impacts:

  • Attention span and focus
  • Sleep quality
  • Social connections
  • Mental health
  • Brain structure and function

Our smartphones and social media apps are designed to be addictive, exploiting the dopamine-driven reward systems in our brains. This constant stimulation and distraction impairs our ability to focus, think deeply, and connect meaningfully with others.

Studies show that excessive screen time is associated with changes in brain structure, particularly in areas related to emotional processing and impulse control. It also disrupts sleep patterns and increases feelings of anxiety and depression. The authors recommend setting boundaries around technology use and cultivating offline activities that enhance prefrontal cortex function.

5. Poor Diet Choices Rewire Our Brains for Addiction and Impulsivity

"Food is, in a real sense, dictating our behaviors!"

A poor diet impacts the brain by:

  • Increasing inflammation
  • Altering gut bacteria composition
  • Disrupting neurotransmitter balance
  • Impairing cognitive function
  • Increasing risk of mood disorders

The modern Western diet, high in refined carbohydrates and processed foods, triggers inflammation and disrupts our gut microbiome. This has far-reaching effects on brain function, including impairing prefrontal cortex activity and strengthening addictive neural pathways.

Highly palatable junk foods activate the brain's reward centers in ways similar to addictive drugs. Over time, this can lead to decreased sensitivity in these circuits, requiring more and more stimulation to achieve the same pleasurable effect. The authors advocate for a diet rich in whole foods, healthy fats, and prebiotic fiber to support optimal brain function and reduce inflammation.

6. Quality Sleep is Essential for Brain Health and Emotional Balance

"Sleep deprivation robs us of our ability to make wise food choices."

Sleep impacts:

  • Memory consolidation
  • Emotional regulation
  • Cognitive performance
  • Inflammation levels
  • Metabolic health

During sleep, our brains undergo critical maintenance and cleanup processes. This includes consolidating memories, clearing out toxins, and regulating neurotransmitter levels. Chronic sleep deprivation disrupts these processes, leading to impaired cognitive function, increased emotional reactivity, and elevated inflammation.

The authors emphasize creating a sleep-supportive environment by:

  • Limiting blue light exposure before bed
  • Maintaining a consistent sleep schedule
  • Creating a cool, dark sleeping environment
  • Avoiding caffeine and alcohol close to bedtime
  • Practicing relaxation techniques before sleep

7. Exercise Enhances Brain Function and Mood Regulation

"Exercise rewires and restructures the brain for better functioning and higher-order thinking."

Exercise benefits the brain by:

  • Increasing blood flow and oxygen to the brain
  • Stimulating production of BDNF (brain-derived neurotrophic factor)
  • Reducing inflammation
  • Improving mood and reducing anxiety/depression
  • Enhancing cognitive function and memory

Physical activity has profound effects on brain health and function. It increases production of BDNF, a protein crucial for neuroplasticity and the growth of new neural connections. Exercise also reduces inflammation and improves insulin sensitivity, both of which support optimal brain function.

Studies show that regular exercise can be as effective as medication for treating mild to moderate depression. It also enhances cognitive functions like attention, memory, and executive control. The authors recommend aiming for at least 30 minutes of moderate exercise most days of the week, with a mix of cardio and strength training.

8. Nature Exposure Reduces Stress and Improves Cognitive Function

"Nature is the ultimate connector. It's our place of origin and our first home."

Nature exposure benefits:

  • Stress reduction
  • Attention restoration
  • Immune function
  • Mood and emotional wellbeing
  • Cognitive performance

Time in nature has been shown to lower cortisol levels, reduce activity in the amygdala, and enhance prefrontal cortex function. It can improve attention and working memory while reducing symptoms of anxiety and depression.

The authors suggest aiming for at least 30 minutes of nature exposure per week, whether that's a walk in a local park, gardening, or simply sitting outside. They also recommend bringing elements of nature indoors with houseplants or nature sounds/images.

9. Mindfulness Practices Strengthen the Prefrontal Cortex

"Mindfulness techniques give you a way to consciously regain control over your thoughts, allowing you to rewire your brain for mental balance and happiness."

Mindfulness benefits:

  • Stress reduction
  • Improved emotional regulation
  • Enhanced attention and focus
  • Increased gray matter in key brain regions
  • Greater self-awareness and compassion

Regular mindfulness practice has been shown to increase gray matter density in the prefrontal cortex and reduce activity in the amygdala. This leads to improved emotional regulation, better stress management, and enhanced cognitive function.

The authors recommend starting with just a few minutes of daily mindfulness practice, such as focused breathing or body scanning. They emphasize that consistency is more important than duration, and that even short periods of mindfulness can yield significant benefits over time.

10. Strong Social Bonds Are Vital for Health, Happiness and Longevity

"Cooperation has been key to our survival as a species. We are happier and longer-lived when we're connected."

Social connections impact:

  • Mental health and wellbeing
  • Physical health and longevity
  • Cognitive function
  • Stress resilience
  • Sense of purpose and meaning

Strong social relationships are one of the most powerful predictors of health, happiness, and longevity. They buffer against stress, improve immune function, and provide a sense of belonging and purpose.

The authors emphasize cultivating deep, meaningful connections over superficial online interactions. They suggest:

  • Prioritizing face-to-face time with loved ones
  • Joining community groups or volunteering
  • Practicing active listening and empathy
  • Limiting social media use in favor of real-world interactions
  • Expressing gratitude and appreciation to others regularly

By nurturing these connections, we create a support network that enhances our resilience and overall wellbeing.

Last updated:

Review Summary

3.80 out of 5
Average of 2k+ ratings from Goodreads and Amazon.

Brain Wash receives mixed reviews, averaging 3.8/5 stars. Some readers find it informative and inspiring, praising its scientific approach to improving mental health and lifestyle habits. Others criticize it for lacking originality, being repetitive, or oversimplifying complex issues. The book covers topics like digital detox, nutrition, sleep, exercise, and meditation. While some appreciate the practical 10-day plan and recipes, others find the suggested changes unrealistic. Critics also question the authors' stance on organic foods and GMOs. Overall, it's considered a good starting point for those new to wellness literature.

Your rating:

About the Author

Dr. David Perlmutter is a Board-Certified Neurologist and four-time New York Times bestselling author. He serves on the American College of Nutrition's Board of Directors and is a Fellow. Dr. David Perlmutter received his M.D. from the University of Miami School of Medicine and has published extensively in peer-reviewed journals. He lectures at prestigious institutions and serves as an Associate Professor at the University of Miami Miller School of Medicine. His books, including the #1 New York Times bestseller "Grain Brain," have been published in 34 languages. Dr. Perlmutter has appeared on numerous television programs and received several awards for his innovative approaches to neurological disorders.

Other books by David Perlmutter

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