🎲 Randomized Trials

Explorations of experimental methodology and its role in producing reliable knowledge across medicine, social science, and public policy. A deep dive into how we learn what actually works.

Snake Oil Science

by R. Barker Bausell • 2007

The pain relief is real; the needle is a prop. How placebo explains alternative medicine.

4.01

346

🧐 Alternative Medicine Skepticism 💊 Placebo Effect 🔬 Clinical Trial Design

Snake Oil Science 89%

The pain relief is real; the needle is a prop. How placebo explains alternative medicine.

by R. Barker Bausell 2007

4.01

346 ratings

🧐 Alternative Medicine Skepticism 💊 Placebo Effect 🔬 Clinical Trial Design

How to Read a Paper

by Trisha Greenhalgh • 1999

From p-values to meta-analyses: critical skills to judge a study, no statistics degree required.

4.02

378

🩺 Evidence-Based Medicine 🔎 Critical Appraisal 🧪 Study Design

How to Read a Paper 89%

From p-values to meta-analyses: critical skills to judge a study, no statistics degree required.

by Trisha Greenhalgh 1999

4.02

378 ratings

🩺 Evidence-Based Medicine 🔎 Critical Appraisal 🧪 Study Design

Surgery, The Ultimate Placebo

by Ian Harris • 2016

Many common surgeries work no better than a fake incision: a surgeon reveals the evidence.

4.16

196

🔬 Evidence-Based Medicine ⚠️ Medical Overtreatment 💊 Placebo Studies

Surgery, The Ultimate Placebo 89%

Many common surgeries work no better than a fake incision: a surgeon reveals the evidence.

by Ian Harris 2016

4.16

196 ratings

🔬 Evidence-Based Medicine ⚠️ Medical Overtreatment 💊 Placebo Studies

Ending Medical Reversal

by Vinayak K. Prasad • 2015

Why standard medical treatments from stents to hormone therapy keep getting overturned.

4.36

407

📊 Evidence-Based Medicine 🧪 Clinical Trials 🔍 Overdiagnosis

Ending Medical Reversal 88%

Why standard medical treatments from stents to hormone therapy keep getting overturned.

by Vinayak K. Prasad 2015

4.36

407 ratings

📊 Evidence-Based Medicine 🧪 Clinical Trials 🔍 Overdiagnosis

Epidemiology

by Leon Gordis • 2000

The epidemiologist's method: how to measure disease, design studies, and prove what causes illness.

3.86

516

📊 Epidemiology 🏥 Public Health 📋 Study Design

Epidemiology 88%

The epidemiologist's method: how to measure disease, design studies, and prove what causes illness.

by Leon Gordis 2000

3.86

516 ratings

📊 Epidemiology 🏥 Public Health 📋 Study Design

Research methods and Statistics in Psychology

by Hugh Coolican • 1990

How to move from hunches to evidence: the full cycle of psychological research, statistics and all.

3.84

194

📊 Psychological Research 📋 Research Methods 🧪 Experimental Design

Research methods and Statistics in Psychology Summary

Research methods and Statistics in Psychology 88%

How to move from hunches to evidence: the full cycle of psychological research, statistics and all.

by Hugh Coolican 1990

3.84

194 ratings

📊 Psychological Research 📋 Research Methods 🧪 Experimental Design

Trick or Treatment

by Simon Singh • 2008

Acupuncture, homeopathy, chiropractic, herbal medicine: held to the evidence, most unravel.

4.11

5k+

💊 Alternative Medicine 🔍 Medical Skepticism 🧪 Clinical Trials

Trick or Treatment 88%

Acupuncture, homeopathy, chiropractic, herbal medicine: held to the evidence, most unravel.

by Simon Singh 2008

4.11

5k+ ratings

💊 Alternative Medicine 🔍 Medical Skepticism 🧪 Clinical Trials

The Seven Deadly Sins of Psychology

by Chris Chambers • 2017

How psychology's methods enable bias, fraud, and shaky results, and the reform that could fix them.

4.41

268

🔬 Research Methods 🔄 Replication Crisis 🔓 Open Science

The Seven Deadly Sins of Psychology Summary

The Seven Deadly Sins of Psychology 88%

How psychology's methods enable bias, fraud, and shaky results, and the reform that could fix them.

by Chris Chambers 2017

4.41

268 ratings

🔬 Research Methods 🔄 Replication Crisis 🔓 Open Science

The Laws of Medicine

by Siddhartha Mukherjee • 2015

Why a strong hunch beats a weak test, and other laws of a science built on uncertainty.

4.07

5k+

🧮 Bayesian Reasoning 🧠 Clinical Reasoning ❓ Medical Uncertainty

The Laws of Medicine 87%

Why a strong hunch beats a weak test, and other laws of a science built on uncertainty.

by Siddhartha Mukherjee 2015

4.07

5k+ ratings

🧮 Bayesian Reasoning 🧠 Clinical Reasoning ❓ Medical Uncertainty

Do You Believe in Magic?

by Paul A. Offit • 2013

A billion-dollar industry runs on loopholes, hope, and the placebo effect, not science.

4.11

3k+

🧪 Alternative Medicine Critique 🩺 Evidence-Based Medicine 🦆 Medical Quackery

Do You Believe in Magic? 87%

A billion-dollar industry runs on loopholes, hope, and the placebo effect, not science.

by Paul A. Offit 2013

4.11

3k+ ratings

🧪 Alternative Medicine Critique 🩺 Evidence-Based Medicine 🦆 Medical Quackery

Pasteur's Quadrant

by Donald E. Stokes • 1997

The report that sold America on funding pure science: the engine of health, security, and growth.

3.82

150

🧪 Science Policy 💰 Research Funding 🧬 Basic Research

Pasteur's Quadrant 87%

The report that sold America on funding pure science: the engine of health, security, and growth.

by Donald E. Stokes 1997

3.82

150 ratings

🧪 Science Policy 💰 Research Funding 🧬 Basic Research

Research Methodology

by C.R. Kothari • 1985

The gap between a research question and a publishable finding, bridged step by step.

3.88

306

🧪 Research Methodology 📊 Quantitative Methods 📐 Research Design

Research Methodology 87%

The gap between a research question and a publishable finding, bridged step by step.

by C.R. Kothari 1985

3.88

306 ratings

🧪 Research Methodology 📊 Quantitative Methods 📐 Research Design

La ciencia pop 2

by Gabriel León • 2018

A tick bite that bans you from steak for life: the science of the body's strangest reactions.

4.13

289

La ciencia pop 2 87%

A tick bite that bans you from steak for life: the science of the body's strangest reactions.

by Gabriel León 2018

4.13

289 ratings

Practical Statistics for Data Scientists

by Peter Bruce • 2017

The statistical methods data scientists use daily, from boxplots to bootstrap, minus the proofs.

4.02

545

🛠️ Practical Data Science 📈 Applied Statistics 🔍 Exploratory Data Analysis

Practical Statistics for Data Scientists Summary

Practical Statistics for Data Scientists 87%

The statistical methods data scientists use daily, from boxplots to bootstrap, minus the proofs.

by Peter Bruce 2017

4.02

545 ratings

🛠️ Practical Data Science 📈 Applied Statistics 🔍 Exploratory Data Analysis

Rational Choice and Security Studies

by Michael E. Brown • 2000

Two visions of political science: one builds mathematical temples, the other wants to stop war.

3.78

🔒 Security Studies 🧮 Rational Choice ⚔️ Methodology Wars

Rational Choice and Security Studies Summary

Rational Choice and Security Studies 87%

Two visions of political science: one builds mathematical temples, the other wants to stop war.

by Michael E. Brown 2000

3.78

9 ratings

🔒 Security Studies 🧮 Rational Choice ⚔️ Methodology Wars

The Art of Statistics

by David Spiegelhalter • 2019

Numbers are mute. How statisticians make them speak, and why p-values and correlation aren't enough.

4.15

6k+

🧮 Statistical Literacy 🔗 Causal Inference 🎲 Bayesian Methods

The Art of Statistics 87%

Numbers are mute. How statisticians make them speak, and why p-values and correlation aren't enough.

by David Spiegelhalter 2019

4.15

6k+ ratings

🧮 Statistical Literacy 🔗 Causal Inference 🎲 Bayesian Methods

Beyond Genetics

by Glenn McGee • 2004

DNA testing, gene therapy, GMOs: what the headlines miss about how they'll actually affect you.

3.60

🧬 Genomics ⚖️ Bioethics 🔬 Genetic Testing

Beyond Genetics 87%

DNA testing, gene therapy, GMOs: what the headlines miss about how they'll actually affect you.

by Glenn McGee 2004

3.60

5 ratings

🧬 Genomics ⚖️ Bioethics 🔬 Genetic Testing

Bad Science

by Ben Goldacre • 2008

From detox footbaths to vaccine panics: how bad science hijacks the headlines and your brain.

4.06

45k+

📰 Science Journalism 🩺 Evidence-Based Medicine 📊 Statistical Literacy

Bad Science 87%

From detox footbaths to vaccine panics: how bad science hijacks the headlines and your brain.

by Ben Goldacre 2008

4.06

45k+ ratings

📰 Science Journalism 🩺 Evidence-Based Medicine 📊 Statistical Literacy

Complications

by Atul Gawande • 2002

Guesswork, uncertainty, and routine error: a surgeon's casebook from inside the operating room.

4.28

53k+

🏥 Surgical Memoir ⚖️ Medical Ethics 📖 Narrative Medicine

Complications 87%

Guesswork, uncertainty, and routine error: a surgeon's casebook from inside the operating room.

by Atul Gawande 2002

4.28

53k+ ratings

🏥 Surgical Memoir ⚖️ Medical Ethics 📖 Narrative Medicine

Epidemiology

by Rodolfo Saracci • 2010

The science that saved cities from cholera and proved tobacco kills, packed into 100 pages.

3.37

351

🏥 Public Health 🗺️ Disease Patterns 🔗 Causal Inference

Epidemiology 87%

The science that saved cities from cholera and proved tobacco kills, packed into 100 pages.

by Rodolfo Saracci 2010

3.37

351 ratings

🏥 Public Health 🗺️ Disease Patterns 🔗 Causal Inference

The Quick Fix

by Jesse Singal • 2021

How psychology's biggest fads escaped the lab, became policy, and did harm, despite the evidence.

3.91

1k+

🧠 Pop Psychology 🔬 Bad Science 🧪 Replication Crisis

The Quick Fix 87%

How psychology's biggest fads escaped the lab, became policy, and did harm, despite the evidence.

by Jesse Singal 2021

3.91

1k+ ratings

🧠 Pop Psychology 🔬 Bad Science 🧪 Replication Crisis

A Survival Guide to the Misinformation Age

by David J. Helfand • 2016

Mental tools from science that let you gut-check any claim yourself, no search engine required.

3.71

220

🧪 Scientific Literacy 🔍 Misinformation Defense 🔢 Quantitative Reasoning

A Survival Guide to the Misinformation Age Summary

A Survival Guide to the Misinformation Age 87%

Mental tools from science that let you gut-check any claim yourself, no search engine required.

by David J. Helfand 2016

3.71

220 ratings

🧪 Scientific Literacy 🔍 Misinformation Defense 🔢 Quantitative Reasoning

Altered Inheritance

by Françoise Baylis • 2019

We can rewrite our children's genes. The danger is letting a few people set the rules.

3.53

🧬 Genome Editing ⚖️ Bioethics 🏛️ Science Policy

Altered Inheritance 87%

We can rewrite our children's genes. The danger is letting a few people set the rules.

by Françoise Baylis 2019

3.53

94 ratings

🧬 Genome Editing ⚖️ Bioethics 🏛️ Science Policy

The Power of Experiments

by Michael Luca • 2020

eBay's experiment killed $50 million in ads. Here's how to run yours.

3.46

246

🧪 Experimental Methods 🧠 Behavioral Economics 📊 A/B Testing

The Power of Experiments 87%

eBay's experiment killed $50 million in ads. Here's how to run yours.

by Michael Luca 2020

3.46

246 ratings

🧪 Experimental Methods 🧠 Behavioral Economics 📊 A/B Testing

The Book of Why

by Judea Pearl • 2018

Data can't tell you why. A mathematical science of cause and effect finally can.

3.93

7k+

🏹 Causal Inference 🕸️ Graphical Models 🔄 Counterfactuals

The Book of Why 87%

Data can't tell you why. A mathematical science of cause and effect finally can.

by Judea Pearl 2018

3.93

7k+ ratings

🏹 Causal Inference 🕸️ Graphical Models 🔄 Counterfactuals

The Math of Life and Death

by Kit Yates • 2019

Key mathematical ideas govern medicine, law, and media, and your intuition gets each one wrong.

3.90

2k+

The Math of Life and Death 87%

Key mathematical ideas govern medicine, law, and media, and your intuition gets each one wrong.

by Kit Yates 2019

3.90

2k+ ratings

Science Fictions

by Stuart Ritchie • 2020

From power posing to cancer cures, how fraud, hype, and broken incentives corrupt science.

4.34

3k+

🧪 Metascience 🔁 Replication Crisis 🕵️ Scientific Misconduct

Science Fictions 87%

From power posing to cancer cures, how fraud, hype, and broken incentives corrupt science.

by Stuart Ritchie 2020

4.34

3k+ ratings

🧪 Metascience 🔁 Replication Crisis 🕵️ Scientific Misconduct

Calculated Risks

by Gerd Gigerenzer • 2002

How to tell when a percentage misleads you, and the reframing that reveals the truth.

3.96

671

📊 Statistical Literacy ⚠️ Risk Communication 🧠 Cognitive Biases

Calculated Risks 87%

How to tell when a percentage misleads you, and the reframing that reveals the truth.

by Gerd Gigerenzer 2002

3.96

671 ratings

📊 Statistical Literacy ⚠️ Risk Communication 🧠 Cognitive Biases

The Great Prostate Hoax

by Richard J. Ablin • 2014

The PSA test generates billions and doesn't save lives. Its discoverer explains how that happened.

4.49

115

🩺 Medical Overdiagnosis 🔬 Cancer Screening 📊 Evidence-Based Medicine

The Great Prostate Hoax 87%

The PSA test generates billions and doesn't save lives. Its discoverer explains how that happened.

by Richard J. Ablin 2014

4.49

115 ratings

🩺 Medical Overdiagnosis 🔬 Cancer Screening 📊 Evidence-Based Medicine

The Norm Chronicles

by Michael Blastland • 2014

Why we fear plane crashes but not burgers: the stories and numbers behind your worst instincts.

3.59

564

🗣️ Risk Communication 🎲 Probability Literacy 🧠 Behavioral Economics

The Norm Chronicles 87%

Why we fear plane crashes but not burgers: the stories and numbers behind your worst instincts.

by Michael Blastland 2014

3.59

564 ratings

🗣️ Risk Communication 🎲 Probability Literacy 🧠 Behavioral Economics

How We Know What Isn't So

by Thomas Gilovich • 1991

The mind finds pattern in noise, then argues for it with absolute conviction.

3.95

3k+

🧠 Cognitive Biases ❤️ Motivated Reasoning 🎲 Randomness Perception

How We Know What Isn't So 87%

The mind finds pattern in noise, then argues for it with absolute conviction.

by Thomas Gilovich 1991

3.95

3k+ ratings

🧠 Cognitive Biases ❤️ Motivated Reasoning 🎲 Randomness Perception

The Victory Lab

by Sasha Issenberg • 2012

How data scientists toppled campaign gurus and built the modern, data-driven political machine.

3.78

2k+

🗳️ Political Campaigns 📊 Data-Driven Politics 🧪 Field Experiments

The Victory Lab 87%

How data scientists toppled campaign gurus and built the modern, data-driven political machine.

by Sasha Issenberg 2012

3.78

2k+ ratings

🗳️ Political Campaigns 📊 Data-Driven Politics 🧪 Field Experiments

Ignorance

by Stuart Firestein • 2012

Science runs on ignorance not facts and the real skill is knowing which question to chase.

3.86

1k+

🧠 Philosophy Of Science 🎓 Science Education 🔬 Scientific Method

Ignorance 87%

Science runs on ignorance not facts and the real skill is knowing which question to chase.

by Stuart Firestein 2012

3.86

1k+ ratings

🧠 Philosophy Of Science 🎓 Science Education 🔬 Scientific Method

Everything Is Predictable

by Tom Chivers • 2024

The math behind your spam filter also reveals that your brain is hallucinating reality.

4.02

1k+

🧮 Bayesian Thinking 🎲 Probability Theory 🧠 Predictive Processing

Everything Is Predictable 87%

The math behind your spam filter also reveals that your brain is hallucinating reality.

by Tom Chivers 2024

4.02

1k+ ratings

🧮 Bayesian Thinking 🎲 Probability Theory 🧠 Predictive Processing

The Emperor of All Maladies

by Siddhartha Mukherjee • 2010

Cancer's biography: a killer that turns out to be a warped reflection of our own biology.

4.34

116k+

📜 Medical History 🔬 Cancer Biology 📖 Disease Biography

The Emperor of All Maladies 87%

Cancer's biography: a killer that turns out to be a warped reflection of our own biology.

by Siddhartha Mukherjee 2010

4.34

116k+ ratings

📜 Medical History 🔬 Cancer Biology 📖 Disease Biography

The Art of Doing Science and Engineering

by Richard W. Hamming • 1996

What separates great scientists from good ones: they pick better problems.

4.18

2k+

🧠 Scientific Thinking ⚙️ Engineering Practice 💻 Computational Thinking

The Art of Doing Science and Engineering Summary

The Art of Doing Science and Engineering 87%

What separates great scientists from good ones: they pick better problems.

by Richard W. Hamming 1996

4.18

2k+ ratings

🧠 Scientific Thinking ⚙️ Engineering Practice 💻 Computational Thinking

How to Read Numbers

by Tom Chivers • 2021

Missing denominators, tiny samples, and the WWII plane error that bends every news stat.

4.32

478

📊 Statistical Literacy 📰 Media Skepticism ⚠️ Risk Literacy

How to Read Numbers 86%

Missing denominators, tiny samples, and the WWII plane error that bends every news stat.

by Tom Chivers 2021

4.32

478 ratings

📊 Statistical Literacy 📰 Media Skepticism ⚠️ Risk Literacy

This Idea Is Brilliant

by John Brockman • 2018

The overlooked scientific ideas top minds most urgently want you to know, from entropy to emergence.

3.83

662

🧠 Third Culture 🔬 Scientific Method 🪞 Cognitive Biases

This Idea Is Brilliant 86%

The overlooked scientific ideas top minds most urgently want you to know, from entropy to emergence.

by John Brockman 2018

3.83

662 ratings

🧠 Third Culture 🔬 Scientific Method 🪞 Cognitive Biases

Better

by Atul Gawande • 2007

Between what medicine knows and what it does, the stubborn details that close the gap.

4.25

37k+

🩺 Surgical Memoir ⚖️ Medical Ethics 🪖 Battlefield Medicine

Better 86%

Between what medicine knows and what it does, the stubborn details that close the gap.

by Atul Gawande 2007

4.25

37k+ ratings

🩺 Surgical Memoir ⚖️ Medical Ethics 🪖 Battlefield Medicine

How Doctors Think

by Jerome Groopman • 2007

Why doctors misdiagnose, and the simple questions that can stop a cognitive error cold.

3.93

13k+

🧠 Cognitive Biases ⚠️ Medical Error 🩺 Doctor Patient Relationship

How Doctors Think 86%

Why doctors misdiagnose, and the simple questions that can stop a cognitive error cold.

by Jerome Groopman 2007

3.93

13k+ ratings

🧠 Cognitive Biases ⚠️ Medical Error 🩺 Doctor Patient Relationship

The Code Breaker

by Walter Isaacson • 2021

How a bacterial defense system handed us the power to rewrite our own evolution.

4.28

42k+

🧬 Genetic Engineering 🧪 Molecular Biology ⚗️ Biotechnology

The Code Breaker 86%

How a bacterial defense system handed us the power to rewrite our own evolution.

by Walter Isaacson 2021

4.28

42k+ ratings

🧬 Genetic Engineering 🧪 Molecular Biology ⚗️ Biotechnology

Antifragile

by Nassim Nicholas Taleb • 2012

Predicting catastrophe is impossible. Designing a life that profits from chaos is not.

4.10

58k+

🔒 Risk Management 🧩 Systems Thinking 🔄 Trial And Error

Antifragile 86%

Predicting catastrophe is impossible. Designing a life that profits from chaos is not.

by Nassim Nicholas Taleb 2012

4.10

58k+ ratings

🔒 Risk Management 🧩 Systems Thinking 🔄 Trial And Error

The Why Axis

by Uri Gneezy • 2013

When daycare fines made parents later, the real science of incentives began.

3.67

1k+

💡 Behavioral Economics 🔬 Field Experiments 🎯 Incentive Design

The Why Axis 86%

When daycare fines made parents later, the real science of incentives began.

by Uri Gneezy 2013

3.67

1k+ ratings

💡 Behavioral Economics 🔬 Field Experiments 🎯 Incentive Design

The Theory That Would Not Die

by Sharon Bertsch McGrayne • 2011

Statisticians said it was dead. Turing used it to crack Enigma. Computers made it unstoppable.

3.77

3k+

🧮 Bayesian Statistics 📜 History Of Mathematics 🎲 Probability Theory

The Theory That Would Not Die 86%

Statisticians said it was dead. Turing used it to crack Enigma. Computers made it unstoppable.

by Sharon Bertsch McGrayne 2011

3.77

3k+ ratings

🧮 Bayesian Statistics 📜 History Of Mathematics 🎲 Probability Theory

The Numbers Game

by Michael Blastland • 2008

Most numbers in the news mislead you; a few mental habits reveal the real story.

3.65

344

📊 Statistical Literacy 📈 Data Interpretation 🤨 Media Skepticism

The Numbers Game 86%

Most numbers in the news mislead you; a few mental habits reveal the real story.

by Michael Blastland 2008

3.65

344 ratings

📊 Statistical Literacy 📈 Data Interpretation 🤨 Media Skepticism

The Genesis Machine

by Amy Webb • 2022

Life is becoming programmable. The technology is here; the rules for using it are not.

3.94

745

🧬 Synthetic Biology 📋 Science Policy ⚖️ Bioethics

The Genesis Machine 86%

Life is becoming programmable. The technology is here; the rules for using it are not.

by Amy Webb 2022

3.94

745 ratings

🧬 Synthetic Biology 📋 Science Policy ⚖️ Bioethics

Research Design

by John W. Creswell • 1994

Align your philosophy, design, and methods into a single coherent research blueprint.

3.82

3k+

📐 Research Design ✍️ Proposal Writing 🔀 Mixed Methods Research

Research Design 86%

Align your philosophy, design, and methods into a single coherent research blueprint.

by John W. Creswell 1994

3.82

3k+ ratings

📐 Research Design ✍️ Proposal Writing 🔀 Mixed Methods Research

Diagnosis

by Lisa Sanders • 2019

High-tech scans get the glory, but the real diagnostic work starts with a doctor who listens.

4.00

4k+

🧩 Medical Mysteries 🦠 Rare Diseases 🧠 Cognitive Biases

Diagnosis 86%

High-tech scans get the glory, but the real diagnostic work starts with a doctor who listens.

by Lisa Sanders 2019

4.00

4k+ ratings

🧩 Medical Mysteries 🦠 Rare Diseases 🧠 Cognitive Biases

A Crack in Creation

by Jennifer A. Doudna • 2017

The tool to rewrite the human genome came from bacteria. Our wisdom is still catching up.

4.13

7k+

🧬 Gene Editing 🔬 Molecular Biology ⚡ Scientific Discovery

A Crack in Creation 86%

The tool to rewrite the human genome came from bacteria. Our wisdom is still catching up.

by Jennifer A. Doudna 2017

4.13

7k+ ratings

🧬 Gene Editing 🔬 Molecular Biology ⚡ Scientific Discovery

Mind the Science

by Jonathan N. Stea • 2024

How a multi-trillion-dollar industry exploits your cognitive biases to sell fake mental health cures

4.15

257

🏥 Wellness Critique 🔬 Science Literacy 🚩 Pseudoscience Detection

Mind the Science 86%

How a multi-trillion-dollar industry exploits your cognitive biases to sell fake mental health cures

by Jonathan N. Stea 2024

4.15

257 ratings

🏥 Wellness Critique 🔬 Science Literacy 🚩 Pseudoscience Detection

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